Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50084141'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50084141 ((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...) Show SMILES Cc1cccc(\C=C\c2ccccc2)n1 Show InChI InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned metabotropic glutamate receptor 5				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50084141 ((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...) Show SMILES Cc1cccc(\C=C\c2ccccc2)n1 Show InChI InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Universit¿a di Perugia Curated by ChEMBL					Assay Description Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)				J Med Chem 42: 5390-401 (2000) BindingDB Entry DOI: 10.7270/Q2ZG6RGS
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50084141 ((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...) Show SMILES Cc1cccc(\C=C\c2ccccc2)n1 Show InChI InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Inhibition of [3H]MPEP binding to mGluR5 in rat brain membrane				Bioorg Med Chem Lett 16: 3371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.04.032 BindingDB Entry DOI: 10.7270/Q2RV0N9Z
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50084141 ((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...) Show SMILES Cc1cccc(\C=C\c2ccccc2)n1 Show InChI InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...				Bioorg Med Chem Lett 12: 407-9 (2002) BindingDB Entry DOI: 10.7270/Q21C1W6J
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50084141 ((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...) Show SMILES Cc1cccc(\C=C\c2ccccc2)n1 Show InChI InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...				Bioorg Med Chem Lett 12: 407-9 (2002) BindingDB Entry DOI: 10.7270/Q21C1W6J
					More data for this Ligand-Target Pair