Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM50109657 (2-Amino-3-[3-hydroxy-4-(2-hydroxy-phenyl)-isoxazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems. | J Med Chem 45: 988-91 (2002) BindingDB Entry DOI: 10.7270/Q2M32V27 | |||||||||||
More data for this Ligand-Target Pair |