Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50154989'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50154989 (2-[2-(5-Fluoro-biphenyl-3-yl)-2H-tetrazol-5-yl]-py...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)-c1ccccc1 Show InChI InChI=1S/C18H12FN5/c19-15-10-14(13-6-2-1-3-7-13)11-16(12-15)24-22-18(21-23-24)17-8-4-5-9-20-17/h1-12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...				Bioorg Med Chem Lett 14: 5477-80 (2004) Article DOI: 10.1016/j.bmcl.2004.09.011 BindingDB Entry DOI: 10.7270/Q29C6WXB
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50154989 (2-[2-(5-Fluoro-biphenyl-3-yl)-2H-tetrazol-5-yl]-py...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)-c1ccccc1 Show InChI InChI=1S/C18H12FN5/c19-15-10-14(13-6-2-1-3-7-13)11-16(12-15)24-22-18(21-23-24)17-8-4-5-9-20-17/h1-12H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assay				Bioorg Med Chem Lett 14: 5485-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.016 BindingDB Entry DOI: 10.7270/Q21V5DGP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50154989 (2-[2-(5-Fluoro-biphenyl-3-yl)-2H-tetrazol-5-yl]-py...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)-c1ccccc1 Show InChI InChI=1S/C18H12FN5/c19-15-10-14(13-6-2-1-3-7-13)11-16(12-15)24-22-18(21-23-24)17-8-4-5-9-20-17/h1-12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 5 in [Ca2+] flux assay using glutamate (10 uM) as agonist				Bioorg Med Chem Lett 14: 5477-80 (2004) Article DOI: 10.1016/j.bmcl.2004.09.011 BindingDB Entry DOI: 10.7270/Q29C6WXB
					More data for this Ligand-Target Pair