Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50154999'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50154999 (3-Fluoro-5-[5-(1H-imidazol-2-yl)-tetrazol-2-yl]-be...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ncc[nH]1)C#N Show InChI InChI=1S/C11H6FN7/c12-8-3-7(6-13)4-9(5-8)19-17-11(16-18-19)10-14-1-2-15-10/h1-5H,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...				Bioorg Med Chem Lett 14: 5481-4 (2004) Article DOI: 10.1016/j.bmcl.2004.09.018 BindingDB Entry DOI: 10.7270/Q25M657V
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50154999 (3-Fluoro-5-[5-(1H-imidazol-2-yl)-tetrazol-2-yl]-be...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ncc[nH]1)C#N Show InChI InChI=1S/C11H6FN7/c12-8-3-7(6-13)4-9(5-8)19-17-11(16-18-19)10-14-1-2-15-10/h1-5H,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Ability to displace [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from binding to metabotropic glutamate receptor 5 in rat cortical membranes				Bioorg Med Chem Lett 15: 5061-4 (2005) Article DOI: 10.1016/j.bmcl.2005.07.062 BindingDB Entry DOI: 10.7270/Q2GT5MQ0
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50154999 (3-Fluoro-5-[5-(1H-imidazol-2-yl)-tetrazol-2-yl]-be...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ncc[nH]1)C#N Show InChI InChI=1S/C11H6FN7/c12-8-3-7(6-13)4-9(5-8)19-17-11(16-18-19)10-14-1-2-15-10/h1-5H,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro functional activity measured by changes in cytosolic [Ca2+] concentrations against rat metabotropic glutamate receptor 5				Bioorg Med Chem Lett 15: 5061-4 (2005) Article DOI: 10.1016/j.bmcl.2005.07.062 BindingDB Entry DOI: 10.7270/Q2GT5MQ0
					More data for this Ligand-Target Pair