Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50171076'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171076 ((3-Ethoxy-5-phenyl-pyridin-2-yl)-(6-methyl-pyridin...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccccc1 Show InChI InChI=1S/C19H19N3O/c1-3-23-17-12-16(15-9-5-4-6-10-15)13-20-19(17)22-18-11-7-8-14(2)21-18/h4-13H,3H2,1-2H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
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