Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50174210'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50174210 (3-Cyclopropylmethoxy-5-(5-pyridin-2-yl-tetrazol-2-...) Show SMILES N#Cc1cc(OCC2CC2)cc(c1)-n1nnc(n1)-c1ccccn1 Show InChI InChI=1S/C17H14N6O/c18-10-13-7-14(9-15(8-13)24-11-12-4-5-12)23-21-17(20-22-23)16-3-1-2-6-19-16/h1-3,6-9,12H,4-5,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	271	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Ability to displace [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from binding to metabotropic glutamate receptor 5 in rat cortical membranes				Bioorg Med Chem Lett 15: 5061-4 (2005) Article DOI: 10.1016/j.bmcl.2005.07.062 BindingDB Entry DOI: 10.7270/Q2GT5MQ0
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50174210 (3-Cyclopropylmethoxy-5-(5-pyridin-2-yl-tetrazol-2-...) Show SMILES N#Cc1cc(OCC2CC2)cc(c1)-n1nnc(n1)-c1ccccn1 Show InChI InChI=1S/C17H14N6O/c18-10-13-7-14(9-15(8-13)24-11-12-4-5-12)23-21-17(20-22-23)16-3-1-2-6-19-16/h1-3,6-9,12H,4-5,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	975	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro functional activity measured by changes in cytosolic [Ca2+] concentrations against rat metabotropic glutamate receptor 5				Bioorg Med Chem Lett 15: 5061-4 (2005) Article DOI: 10.1016/j.bmcl.2005.07.062 BindingDB Entry DOI: 10.7270/Q2GT5MQ0
					More data for this Ligand-Target Pair