Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50174212'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50174212 (5-(5-Pyridin-2-yl-tetrazol-2-yl)-isophthalonitrile...) Show SMILES N#Cc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)C#N Show InChI InChI=1S/C14H7N7/c15-8-10-5-11(9-16)7-12(6-10)21-19-14(18-20-21)13-3-1-2-4-17-13/h1-7H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Ability to displace [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from binding to metabotropic glutamate receptor 5 in rat cortical membranes				Bioorg Med Chem Lett 15: 5061-4 (2005) Article DOI: 10.1016/j.bmcl.2005.07.062 BindingDB Entry DOI: 10.7270/Q2GT5MQ0
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50174212 (5-(5-Pyridin-2-yl-tetrazol-2-yl)-isophthalonitrile...) Show SMILES N#Cc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)C#N Show InChI InChI=1S/C14H7N7/c15-8-10-5-11(9-16)7-12(6-10)21-19-14(18-20-21)13-3-1-2-4-17-13/h1-7H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro functional activity measured by changes in cytosolic [Ca2+] concentrations against rat metabotropic glutamate receptor 5				Bioorg Med Chem Lett 15: 5061-4 (2005) Article DOI: 10.1016/j.bmcl.2005.07.062 BindingDB Entry DOI: 10.7270/Q2GT5MQ0
					More data for this Ligand-Target Pair