Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50187637'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50187637 (CHEMBL382766 | N-(1-phenyl-3-(2-chlorophenyl)-1H-p...) Show SMILES Clc1ccccc1-c1cc(NC(=O)c2ccccc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C22H16ClN3O/c23-19-14-8-7-13-18(19)20-15-21(24-22(27)16-9-3-1-4-10-16)26(25-20)17-11-5-2-6-12-17/h1-15H,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cells				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50187637 (CHEMBL382766 | N-(1-phenyl-3-(2-chlorophenyl)-1H-p...) Show SMILES Clc1ccccc1-c1cc(NC(=O)c2ccccc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C22H16ClN3O/c23-19-14-8-7-13-18(19)20-15-21(24-22(27)16-9-3-1-4-10-16)26(25-20)17-11-5-2-6-12-17/h1-15H,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytes				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair