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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50187651'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50187651
PNG
(CHEMBL207814 | N-(1-(2-pyridyl)-3-phenyl-1H-pyrazo...)
Show SMILES O=C(Nc1cc(nn1-c1ccccn1)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C21H16N4O/c26-21(17-11-5-2-6-12-17)23-20-15-18(16-9-3-1-4-10-16)24-25(20)19-13-7-8-14-22-19/h1-15H,(H,23,26)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Vanderbilt University School of Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cells

J Med Chem 49: 3332-44 (2006)


Article DOI: 10.1021/jm051252j
BindingDB Entry DOI: 10.7270/Q2PR7VK1
More data for this
Ligand-Target Pair