Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50214070'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50214070 (6-methyl-1,5-di(pyrazin-2-yl)-1H-pyrazolo[3,4-d]py...) Show SMILES Cc1nc2n(ncc2c(=O)n1-c1cnccn1)-c1cnccn1 Show InChI InChI=1S/C14H10N8O/c1-9-20-13-10(6-19-22(13)12-8-16-3-5-18-12)14(23)21(9)11-7-15-2-4-17-11/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 receptor expressed in 132N1 cells assessed as inhibition of glutamate-induced calcium flux by FLIPR assay				Bioorg Med Chem Lett 17: 4303-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.028 BindingDB Entry DOI: 10.7270/Q2445M5T
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