Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50305044'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50305044 ((5-chloro-6-(6-methylpyridin-3-ylamino)pyridin-3-y...) Show SMILES Cc1ccc(Nc2ncc(cc2Cl)C(=O)N2CCCCC2)cn1 Show InChI InChI=1S/C17H19ClN4O/c1-12-5-6-14(11-19-12)21-16-15(18)9-13(10-20-16)17(23)22-7-3-2-4-8-22/h5-6,9-11H,2-4,7-8H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 assessed as inhibition of glutamate-induced elevation of intracellular calcium concentration				Bioorg Med Chem Lett 20: 184-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.001 BindingDB Entry DOI: 10.7270/Q2QN66VN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50305044 ((5-chloro-6-(6-methylpyridin-3-ylamino)pyridin-3-y...) Show SMILES Cc1ccc(Nc2ncc(cc2Cl)C(=O)N2CCCCC2)cn1 Show InChI InChI=1S/C17H19ClN4O/c1-12-5-6-14(11-19-12)21-16-15(18)9-13(10-20-16)17(23)22-7-3-2-4-8-22/h5-6,9-11H,2-4,7-8H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	258	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 assessed as inhibition of quisqualate-induced intracellular inositol phosphate accumulation				Bioorg Med Chem Lett 20: 184-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.001 BindingDB Entry DOI: 10.7270/Q2QN66VN
					More data for this Ligand-Target Pair