Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50323386'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323386 (1,2-dicyclohexyl-3-(2-methyl-1H-imidazol-1-yl)prop...) Show SMILES Cc1nccn1CC(C1CCCCC1)C(=N\OC(=O)Nc1cccc(Cl)c1)\C1CCCCC1 Show InChI InChI=1S/C26H35ClN4O2/c1-19-28-15-16-31(19)18-24(20-9-4-2-5-10-20)25(21-11-6-3-7-12-21)30-33-26(32)29-23-14-8-13-22(27)17-23/h8,13-17,20-21,24H,2-7,9-12,18H2,1H3,(H,29,32)/b30-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
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