Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50416278'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416278 (CHEMBL1082328) Show SMILES O=C(N1CCCCC1c1nc(no1)-c1cccc(c1)C#N)c1cccs1 Show InChI InChI=1S/C19H16N4O2S/c20-12-13-5-3-6-14(11-13)17-21-18(25-22-17)15-7-1-2-9-23(15)19(24)16-8-4-10-26-16/h3-6,8,10-11,15H,1-2,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416278 (CHEMBL1082328) Show SMILES O=C(N1CCCCC1c1nc(no1)-c1cccc(c1)C#N)c1cccs1 Show InChI InChI=1S/C19H16N4O2S/c20-12-13-5-3-6-14(11-13)17-21-18(25-22-17)15-7-1-2-9-23(15)19(24)16-8-4-10-26-16/h3-6,8,10-11,15H,1-2,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium level				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair