Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50429420'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50429420 (CHEMBL2338565) Show SMILES Fc1ccccc1C(=O)N[C@H]1CCC[C@@H](C1)NC(=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H20ClFN2O2/c21-14-6-3-5-13(11-14)19(25)23-15-7-4-8-16(12-15)24-20(26)17-9-1-2-10-18(17)22/h1-3,5-6,9-11,15-16H,4,7-8,12H2,(H,23,25)(H,24,26)/t15-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 23: 1398-406 (2013) Article DOI: 10.1016/j.bmcl.2012.12.078 BindingDB Entry DOI: 10.7270/Q2Q241KC
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Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50429420 (CHEMBL2338565) Show SMILES Fc1ccccc1C(=O)N[C@H]1CCC[C@@H](C1)NC(=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H20ClFN2O2/c21-14-6-3-5-13(11-14)19(25)23-15-7-4-8-16(12-15)24-20(26)17-9-1-2-10-18(17)22/h1-3,5-6,9-11,15-16H,4,7-8,12H2,(H,23,25)(H,24,26)/t15-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assay				Bioorg Med Chem Lett 23: 1398-406 (2013) Article DOI: 10.1016/j.bmcl.2012.12.078 BindingDB Entry DOI: 10.7270/Q2Q241KC
					More data for this Ligand-Target Pair