Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM66976 ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PubMed | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned metabotropic glutamate receptor 5 | J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM66976 ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article | n/a | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for the agonistic activity against Metabotropic glutamate receptor 5 | Bioorg Med Chem Lett 7: 601-606 (1997) Article DOI: 10.1016/S0960-894X(97)00068-1 BindingDB Entry DOI: 10.7270/Q27944QG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM66976 ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 5 | J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM66976 ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a |
Università degli Studi di Milano Curated by ChEMBL | Assay Description Activity of the compound tested at cloned rat Metabotropic glutamate receptor 5 expressed in Chinese Hamster Ovary (CHO) cells | J Med Chem 46: 3102-8 (2003) Article DOI: 10.1021/jm0308085 BindingDB Entry DOI: 10.7270/Q2X34WWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM66976 ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a |
CNS Research Curated by ChEMBL | Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR5a in rat | J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R | |||||||||||
More data for this Ligand-Target Pair |