Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metallo-beta-lactamase IMP-1' and Ligand = 'BDBM50493083'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase IMP-1 (Pseudomonas aeruginosa)	BDBM50493083 (CHEMBL2420948) Show SMILES OC(=O)c1cccc(N2CCC(O)(CC2)c2ccccc2)c1C(O)=O Show InChI InChI=1S/C19H19NO5/c21-17(22)14-7-4-8-15(16(14)18(23)24)20-11-9-19(25,10-12-20)13-5-2-1-3-6-13/h1-8,25H,9-12H2,(H,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Pharma, Co., Ltd Curated by ChEMBL					Assay Description Inhibition of carbapenems-resistant Pseudomonas aeruginosa MSC15369 metallo-beta-lactamase IMP1 expressed in Escherichia coli DH5[alpha] using nitroc...				Bioorg Med Chem 21: 5841-50 (2013) Article DOI: 10.1016/j.bmc.2013.07.006 BindingDB Entry DOI: 10.7270/Q24X5BQM
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