Found 4 hits Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 1' and Ligand = 'BDBM50121347' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
![PNG](/data/jpeg/tenK5012/BindingDB_50121347.png) (CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Heidelberg
Curated by ChEMBL
| Assay Description Inhibition of human MetAP1 |
Bioorg Med Chem Lett 20: 4038-44 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.093 BindingDB Entry DOI: 10.7270/Q2RF5W0K |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
![PNG](/data/jpeg/tenK5012/BindingDB_50121347.png) (CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Mn2+ |
J Med Chem 56: 3996-4016 (2013)
Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
![PNG](/data/jpeg/tenK5012/BindingDB_50121347.png) (CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+ |
J Med Chem 56: 3996-4016 (2013)
Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
![PNG](/data/jpeg/tenK5012/BindingDB_50121347.png) (CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Zn2+ |
J Med Chem 56: 3996-4016 (2013)
Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z |
More data for this Ligand-Target Pair | |