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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 1' and Ligand = 'BDBM50169664'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50169664
PNG
(5-(2-Methoxy-propyl)-thiazole-4-carboxylic acid th...)
Show SMILES COC(C)Cc1scnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C11H13N3O2S2/c1-7(16-2)5-8-9(13-6-18-8)10(15)14-11-12-3-4-17-11/h3-4,6-7H,5H2,1-2H3,(H,12,14,15)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 880n/an/an/an/an/an/a



Graduate School of the Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)


Bioorg Med Chem Lett 15: 3732-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.055
BindingDB Entry DOI: 10.7270/Q2T1534B
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50169664
PNG
(5-(2-Methoxy-propyl)-thiazole-4-carboxylic acid th...)
Show SMILES COC(C)Cc1scnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C11H13N3O2S2/c1-7(16-2)5-8-9(13-6-18-8)10(15)14-11-12-3-4-17-11/h3-4,6-7H,5H2,1-2H3,(H,12,14,15)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 880n/an/an/an/an/an/a



Shanghai Graduate School of the Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against ScMetAP1 enzyme activity


Bioorg Med Chem Lett 15: 4130-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.005
BindingDB Entry DOI: 10.7270/Q2FN15RH
More data for this
Ligand-Target Pair