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Found 1 hit Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 1' and Ligand = 'BDBM50169684'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50169684
PNG
(5-(2-Chloro-4-fluoro-benzyl)-thiazole-4-carboxylic...)
Show SMILES Fc1ccc(Cc2scnc2C(=O)Nc2nccs2)c(Cl)c1
Show InChI InChI=1S/C14H9ClFN3OS2/c15-10-6-9(16)2-1-8(10)5-11-12(18-7-22-11)13(20)19-14-17-3-4-21-14/h1-4,6-7H,5H2,(H,17,19,20)
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Similars

Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Graduate School of the Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)


Bioorg Med Chem Lett 15: 3732-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.055
BindingDB Entry DOI: 10.7270/Q2T1534B
More data for this
Ligand-Target Pair