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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 2' and Ligand = 'BDBM50147357'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM50147357
PNG
((R)-3-(S)-Amino-2-hydroxy-4-phenyl-N-{4-[3-((E)-3,...)
Show SMILES COc1cc(\C=C\C(=O)Nc2ccc(NC(=O)[C@@H](O)[C@H](N)Cc3ccccc3)cc2)cc(OC)c1OC
Show InChI InChI=1S/C28H31N3O6/c1-35-23-16-19(17-24(36-2)27(23)37-3)9-14-25(32)30-20-10-12-21(13-11-20)31-28(34)26(33)22(29)15-18-7-5-4-6-8-18/h4-14,16-17,22,26,33H,15,29H2,1-3H3,(H,30,32)(H,31,34)/b14-9+/t22-,26+/m1/s1
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PC cid
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Article
PubMed
n/an/a 755n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of human MetAP2


Eur J Med Chem 173: 213-227 (2019)


Article DOI: 10.1016/j.ejmech.2019.04.009
BindingDB Entry DOI: 10.7270/Q26M3B56
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM50147357
PNG
((R)-3-(S)-Amino-2-hydroxy-4-phenyl-N-{4-[3-((E)-3,...)
Show SMILES COc1cc(\C=C\C(=O)Nc2ccc(NC(=O)[C@@H](O)[C@H](N)Cc3ccccc3)cc2)cc(OC)c1OC
Show InChI InChI=1S/C28H31N3O6/c1-35-23-16-19(17-24(36-2)27(23)37-3)9-14-25(32)30-20-10-12-21(13-11-20)31-28(34)26(33)22(29)15-18-7-5-4-6-8-18/h4-14,16-17,22,26,33H,15,29H2,1-3H3,(H,30,32)(H,31,34)/b14-9+/t22-,26+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 755n/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
In vitro inhibition of human recombinant Methionine aminopeptidase 2.


Bioorg Med Chem Lett 14: 3181-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.004
BindingDB Entry DOI: 10.7270/Q2J38S1M
More data for this
Ligand-Target Pair