Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Methylosome protein 50/Protein arginine N-methyltransferase 5' and Ligand = 'BDBM343957'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM343957 (1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-((4-(1-(tetr...) Show SMILES OC(CNc1cc(ccn1)-c1ccc2ncn(C3CCOCC3)c2c1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C29H33N5O2/c35-26(19-33-12-8-21-3-1-2-4-24(21)18-33)17-31-29-16-23(7-11-30-29)22-5-6-27-28(15-22)34(20-32-27)25-9-13-36-14-10-25/h1-7,11,15-16,20,25-26,35H,8-10,12-14,17-19H2,(H,30,31)	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9777008 (2017) BindingDB Entry DOI: 10.7270/Q26975QQ
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