Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human)) | BDBM415529 ((Scheme R) (2R,3R,4S,5R)-2-(4-amino-5-fluoro-7H-py...) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Prelude Therapeutics Curated by ChEMBL | Assay Description Inhibition of full length N-terminal FLAG-tagged PRMT5 (unknown origin)/MEP50 (unknown origin) expressed in baculovirus infected Sf21 insect cells us... | Bioorg Med Chem Lett 29: 1264-1269 (2019) Article DOI: 10.1016/j.bmcl.2019.03.042 BindingDB Entry DOI: 10.7270/Q2ZC869N | |||||||||||
More data for this Ligand-Target Pair |