Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Methylosome protein 50/Protein arginine N-methyltransferase 5' and Ligand = 'BDBM50523643'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50523643 (CHEMBL4454890) Show SMILES Nc1cccc(CCCC[C@H]2C[C@H]([C@H](O)[C@@H]2O)n2ccc3c(N)ncnc23)n1 |r| Show InChI InChI=1S/C20H26N6O2/c21-16-7-3-6-13(25-16)5-2-1-4-12-10-15(18(28)17(12)27)26-9-8-14-19(22)23-11-24-20(14)26/h3,6-9,11-12,15,17-18,27-28H,1-2,4-5,10H2,(H2,21,25)(H2,22,23,24)/t12-,15+,17+,18-/m0/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Prelude Therapeutics Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal FLAG-tagged PRMT5/full length N-terminal His6-tagged MEP50 (unknown origin) expressed in baculovirus infec...				Bioorg Med Chem Lett 29: 1264-1269 (2019) Article DOI: 10.1016/j.bmcl.2019.03.042 BindingDB Entry DOI: 10.7270/Q2ZC869N
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