Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microsomal triglyceride transfer protein large subunit' and Ligand = 'BDBM50184125'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein large subunit (Homo sapiens (Human))	BDBM50184125 (1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-piperid...) Show SMILES CCCN(CC)C(=O)[C@@H](NC(=O)C1CCN(CC1)C(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C33H36F3N3O3/c1-3-20-38(4-2)32(42)29(24-10-6-5-7-11-24)37-30(40)25-18-21-39(22-19-25)31(41)28-13-9-8-12-27(28)23-14-16-26(17-15-23)33(34,35)36/h5-17,25,29H,3-4,18-22H2,1-2H3,(H,37,40)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.43	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MTP in canine liver microsomes				Bioorg Med Chem Lett 16: 3039-42 (2006) Article DOI: 10.1016/j.bmcl.2006.02.058 BindingDB Entry DOI: 10.7270/Q2D21X68
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