Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor' and Ligand = 'BDBM50359641'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359641 (CHEMBL1928874) Show SMILES Fc1ccccc1C1Sc2nncn2N=C1c1ccc2OCC(=O)Nc2c1 |c:16| Show InChI InChI=1S/C18H12FN5O2S/c19-12-4-2-1-3-11(12)17-16(23-24-9-20-22-18(24)27-17)10-5-6-14-13(7-10)21-15(25)8-26-14/h1-7,9,17H,8H2,(H,21,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
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