Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM318361'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM318361 (US10301317, Example 318 | US9624228, Example 318) Show SMILES CC(c1ccccc1)c1cc2cc3c(n[nH]c3cc2[nH]c1=O)-c1ccnc(c1)N1CCN(C)CC1 Show InChI InChI=1S/C28H26N6O/c1-18(19-6-4-3-5-7-19)22-14-21-15-23-25(17-24(21)30-28(22)35)31-32-27(23)20-8-9-29-26(16-20)34-12-10-33(2)11-13-34/h3-9,14-18H,10-13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2GM89M0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM318361 (US10301317, Example 318 | US9624228, Example 318) Show SMILES CC(c1ccccc1)c1cc2cc3c(n[nH]c3cc2[nH]c1=O)-c1ccnc(c1)N1CCN(C)CC1 Show InChI InChI=1S/C28H26N6O/c1-18(19-6-4-3-5-7-19)22-14-21-15-23-25(17-24(21)30-28(22)35)31-32-27(23)20-8-9-29-26(16-20)34-12-10-33(2)11-13-34/h3-9,14-18H,10-13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Kura Oncology, Inc. US Patent					Assay Description The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...				US Patent US9624228 (2017) BindingDB Entry DOI: 10.7270/Q22809PP
					More data for this Ligand-Target Pair