Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM318375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM318375 (US10301317, Example 332 | US9624228, Example 332) Show SMILES Cc1cc(ccn1)-c1n[nH]c2cc3[nH]c(=O)c(cc3cc12)C1CCCN(Cc2ccccc2)C1 Show InChI InChI=1S/C28H25N5O/c1-18-12-20(9-10-29-18)27-24-14-22-13-23(28(34)30-25(22)15-26(24)31-32-27)21-8-5-11-33(17-21)16-19-6-3-2-4-7-19/h2-4,6-7,9-10,12-15,21H,5,8,11,16-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2GM89M0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM318375 (US10301317, Example 332 | US9624228, Example 332) Show SMILES Cc1cc(ccn1)-c1n[nH]c2cc3[nH]c(=O)c(cc3cc12)C1CCCN(Cc2ccccc2)C1 Show InChI InChI=1S/C28H25N5O/c1-18-12-20(9-10-29-18)27-24-14-22-13-23(28(34)30-25(22)15-26(24)31-32-27)21-8-5-11-33(17-21)16-19-6-3-2-4-7-19/h2-4,6-7,9-10,12-15,21H,5,8,11,16-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Kura Oncology, Inc. US Patent					Assay Description The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...				US Patent US9624228 (2017) BindingDB Entry DOI: 10.7270/Q22809PP
					More data for this Ligand-Target Pair