Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10/8/9' and Ligand = 'BDBM50506726'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10/8/9 (Homo sapiens (Human))	BDBM50506726 (CHEMBL4524938) Show SMILES CCOc1ccc2nc3\C(=N/O)c4ccccc4-c3nc2c1 Show InChI InChI=1S/C17H13N3O2/c1-2-22-10-7-8-13-14(9-10)19-15-11-5-3-4-6-12(11)16(20-21)17(15)18-13/h3-9,21H,2H2,1H3/b20-16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University Curated by ChEMBL					Assay Description Inhibition of JNK in human THP1-Blue cells assessed as reduction in LPS-induced NFkappaB/AP1 activation preincubated for 30 mins followed by LPS-stim...				Eur J Med Chem 161: 179-191 (2019) Article DOI: 10.1016/j.ejmech.2018.10.023 BindingDB Entry DOI: 10.7270/Q2TB1B58
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/8/9 (Homo sapiens (Human))	BDBM50506726 (CHEMBL4524938) Show SMILES CCOc1ccc2nc3\C(=N/O)c4ccccc4-c3nc2c1 Show InChI InChI=1S/C17H13N3O2/c1-2-22-10-7-8-13-14(9-10)19-15-11-5-3-4-6-12(11)16(20-21)17(15)18-13/h3-9,21H,2H2,1H3/b20-16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University Curated by ChEMBL					Assay Description Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production preincubated for 30 mins followed by LPS-stimulation ...				Eur J Med Chem 161: 179-191 (2019) Article DOI: 10.1016/j.ejmech.2018.10.023 BindingDB Entry DOI: 10.7270/Q2TB1B58
					More data for this Ligand-Target Pair