Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11/12/13/14' and Ligand = 'BDBM50474811'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50474811 (CHEMBL316065) Show SMILES COC[C@H](C)Nc1nccc(n1)-c1c(-c2ccc(F)cc2)c(=O)n2CCCn12 Show InChI InChI=1S/C20H22FN5O2/c1-13(12-28-2)23-20-22-9-8-16(24-20)18-17(14-4-6-15(21)7-5-14)19(27)26-11-3-10-25(18)26/h4-9,13H,3,10-12H2,1-2H3,(H,22,23,24)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of LPS-stimulated p38-related TNF-alpha production in human peripheral blood mononuclear cells (PBMC)				J Med Chem 47: 2724-7 (2004) Article DOI: 10.1021/jm049968m BindingDB Entry DOI: 10.7270/Q2ZC85NQ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50474811 (CHEMBL316065) Show SMILES COC[C@H](C)Nc1nccc(n1)-c1c(-c2ccc(F)cc2)c(=O)n2CCCn12 Show InChI InChI=1S/C20H22FN5O2/c1-13(12-28-2)23-20-22-9-8-16(24-20)18-17(14-4-6-15(21)7-5-14)19(27)26-11-3-10-25(18)26/h4-9,13H,3,10-12H2,1-2H3,(H,22,23,24)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human Mitogen-activated protein kinase p38				J Med Chem 47: 2724-7 (2004) Article DOI: 10.1021/jm049968m BindingDB Entry DOI: 10.7270/Q2ZC85NQ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50474811 (CHEMBL316065) Show SMILES COC[C@H](C)Nc1nccc(n1)-c1c(-c2ccc(F)cc2)c(=O)n2CCCn12 Show InChI InChI=1S/C20H22FN5O2/c1-13(12-28-2)23-20-22-9-8-16(24-20)18-17(14-4-6-15(21)7-5-14)19(27)26-11-3-10-25(18)26/h4-9,13H,3,10-12H2,1-2H3,(H,22,23,24)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of LPS-stimulated p38-related IL1-beta production in human peripheral blood mononuclear cells (PBMC)				J Med Chem 47: 2724-7 (2004) Article DOI: 10.1021/jm049968m BindingDB Entry DOI: 10.7270/Q2ZC85NQ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50474811 (CHEMBL316065) Show SMILES COC[C@H](C)Nc1nccc(n1)-c1c(-c2ccc(F)cc2)c(=O)n2CCCn12 Show InChI InChI=1S/C20H22FN5O2/c1-13(12-28-2)23-20-22-9-8-16(24-20)18-17(14-4-6-15(21)7-5-14)19(27)26-11-3-10-25(18)26/h4-9,13H,3,10-12H2,1-2H3,(H,22,23,24)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)				J Med Chem 47: 2724-7 (2004) Article DOI: 10.1021/jm049968m BindingDB Entry DOI: 10.7270/Q2ZC85NQ
					More data for this Ligand-Target Pair