Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11/12/13/14' and Ligand = 'BDBM50474813'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50474813 (CHEMBL328077) Show SMILES C[C@H](Nc1nccc(n1)-c1c(-c2ccc(F)cc2)c(=O)n2CCCn12)c1ccc(C)cc1 Show InChI InChI=1S/C25H24FN5O/c1-16-4-6-18(7-5-16)17(2)28-25-27-13-12-21(29-25)23-22(19-8-10-20(26)11-9-19)24(32)31-15-3-14-30(23)31/h4-13,17H,3,14-15H2,1-2H3,(H,27,28,29)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)				J Med Chem 47: 2724-7 (2004) Article DOI: 10.1021/jm049968m BindingDB Entry DOI: 10.7270/Q2ZC85NQ
					More data for this Ligand-Target Pair