Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM125996'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM125996 (US8772288, 37) Show SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC(C)(O)CC2)c1)C(=O)NC1CC1 |(-4.1,1.56,;-2.77,2.33,;-2.77,3.87,;-1.44,4.64,;-.1,3.87,;-.1,2.33,;-1.44,1.56,;-1.44,.02,;-.1,-.75,;-.1,-2.29,;-1.44,-3.06,;-2.77,-2.29,;-3.91,-3.32,;-3.29,-4.73,;-4.06,-6.06,;-1.76,-4.57,;-2.16,-6.05,;-1.07,-7.14,;.42,-6.74,;.42,-8.28,;1.91,-7.14,;.82,-5.26,;-.27,-4.17,;-2.77,-.75,;1.23,4.64,;2.56,3.87,;1.23,6.18,;2.56,6.95,;4.1,6.95,;3.33,8.28,)| Show InChI InChI=1S/C25H28N2O3/c1-15-3-4-17(22(28)26-18-6-7-18)13-19(15)16-5-8-20-21(14-16)27-23(29)25(20)11-9-24(2,30)10-12-25/h3-5,8,13-14,18,30H,6-7,9-12H2,1-2H3,(H,26,28)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	25
Almirall, S.A. US Patent					Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...				US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM
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