Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM125997'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM125997 (US8772288, 40) Show SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC(CC2)N2CCOCC2)c1)C(=O)NC1CC1 |(-4.77,3.67,;-3.44,4.44,;-3.44,5.98,;-2.1,6.75,;-.77,5.98,;-.77,4.44,;-2.1,3.67,;-2.1,2.13,;-.77,1.36,;-.77,-.18,;-2.1,-.95,;-3.44,-.18,;-4.58,-1.21,;-3.96,-2.61,;-4.73,-3.95,;-2.42,-2.45,;-2.82,-3.94,;-1.73,-5.03,;-.25,-4.63,;.15,-3.14,;-.94,-2.05,;.84,-5.72,;.44,-7.21,;1.53,-8.29,;3.02,-7.9,;3.42,-6.41,;2.33,-5.32,;-3.44,1.36,;.56,6.75,;.56,8.29,;1.9,5.98,;3.23,6.75,;4,8.09,;4.77,6.75,)| Show InChI InChI=1S/C28H33N3O3/c1-18-2-3-20(26(32)29-21-5-6-21)16-23(18)19-4-7-24-25(17-19)30-27(33)28(24)10-8-22(9-11-28)31-12-14-34-15-13-31/h2-4,7,16-17,21-22H,5-6,8-15H2,1H3,(H,29,32)(H,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Almirall, S.A. US Patent					Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...				US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM
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