Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM126000'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM126000 (US8772288, 65) Show SMILES Cc1nnc([nH]1)-c1cc(F)c(C)c(c1)-c1ccc2c(NC(=O)C22CCC(C)(O)CC2)c1 |(3.72,8.14,;2.95,6.8,;3.85,5.56,;2.95,4.31,;1.48,4.79,;1.48,6.33,;.15,4.02,;-1.18,4.79,;-2.52,4.02,;-3.85,4.79,;-2.52,2.48,;-3.85,1.71,;-1.18,1.71,;.15,2.48,;-1.18,.17,;.15,-.6,;.15,-2.14,;-1.18,-2.91,;-2.52,-2.14,;-3.66,-3.17,;-3.04,-4.58,;-3.81,-5.91,;-1.51,-4.42,;-1.9,-5.91,;-.81,-7,;.67,-6.6,;.67,-8.14,;2.01,-7.37,;1.07,-5.11,;-.02,-4.02,;-2.52,-.6,)| Show InChI InChI=1S/C24H25FN4O2/c1-13-17(10-16(11-19(13)25)21-26-14(2)28-29-21)15-4-5-18-20(12-15)27-22(30)24(18)8-6-23(3,31)7-9-24/h4-5,10-12,31H,6-9H2,1-3H3,(H,27,30)(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
Almirall, S.A. US Patent					Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...				US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM
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