Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM354293'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM354293 (1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...) Show SMILES Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(cc4)P(C)(C)=O)C(C)(C)C)c4ccccc34)n2)cc2cn[nH]c12 Show InChI InChI=1S/C38H38N9O3P/c1-23-19-25(20-24-22-40-45-35(23)24)41-36-39-18-17-34(44-36)50-31-16-15-30(28-9-7-8-10-29(28)31)42-37(48)43-33-21-32(38(2,3)4)46-47(33)26-11-13-27(14-12-26)51(5,6)49/h7-22H,1-6H3,(H,40,45)(H,39,41,44)(H2,42,43,48)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Limited; Topivert Pharma Limited US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...				US Patent US9796742 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J5M
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