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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM354310'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM354310
PNG
(3-((4-((4-(3-(1-(3-((Dimethylphosphoryl)methyl)phe...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CP(C)(C)=O)c4)C(C)C)c4ccccc34)n2)cc(c1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C44H50N9O6P/c1-29(2)38-27-40(53(51-38)33-10-8-9-30(23-33)28-60(4,5)56)49-44(55)48-37-13-14-39(36-12-7-6-11-35(36)37)59-41-15-16-46-43(50-41)47-32-24-31(25-34(26-32)57-3)42(54)45-17-18-52-19-21-58-22-20-52/h6-16,23-27,29H,17-22,28H2,1-5H3,(H,45,54)(H,46,47,50)(H2,48,49,55)
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US Patent
n/an/a 10n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...

US Patent US9796742 (2017)


BindingDB Entry DOI: 10.7270/Q2KW5J5M
More data for this
Ligand-Target Pair