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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM354311'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM354311
PNG
(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CP(C)(C)=O)c4)C(C)C)c4ccccc34)n2)cc(OCCN2CCOCC2)c1
Show InChI InChI=1S/C43H49N8O6P/c1-29(2)38-27-40(51(49-38)32-10-8-9-30(23-32)28-58(4,5)53)47-43(52)46-37-13-14-39(36-12-7-6-11-35(36)37)57-41-15-16-44-42(48-41)45-31-24-33(54-3)26-34(25-31)56-22-19-50-17-20-55-21-18-50/h6-16,23-27,29H,17-22,28H2,1-5H3,(H,44,45,48)(H2,46,47,52)
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US Patent
n/an/a 13n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...

US Patent US9796742 (2017)


BindingDB Entry DOI: 10.7270/Q2KW5J5M
More data for this
Ligand-Target Pair