Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM354317'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM354317 (1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...) Show SMILES COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CP(C)(C)=O)c4)C(C)C)c4ccccc34)n2)cc(OC)c1 Show InChI InChI=1S/C44H52N7O8P/c1-30(2)39-28-41(51(50-39)33-11-9-10-31(24-33)29-60(5,6)53)48-44(52)47-38-14-15-40(37-13-8-7-12-36(37)38)59-42-16-17-45-43(49-42)46-32-25-34(55-4)27-35(26-32)58-23-22-57-21-20-56-19-18-54-3/h7-17,24-28,30H,18-23,29H2,1-6H3,(H,45,46,49)(H2,47,48,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Limited; Topivert Pharma Limited US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...				US Patent US9796742 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J5M
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