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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM354322'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM354322
PNG
(3-((4-((4-(3-(1-(3-((Dimethylphosphoryl)methyl)phe...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CP(C)(C)=O)c4)C(C)C)c4ccccc34)ccn2)cc(c1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C45H51N8O6P/c1-30(2)40-28-43(53(51-40)34-10-8-9-31(23-34)29-60(4,5)56)50-45(55)49-39-13-14-41(38-12-7-6-11-37(38)39)59-35-15-16-46-42(27-35)48-33-24-32(25-36(26-33)57-3)44(54)47-17-18-52-19-21-58-22-20-52/h6-16,23-28,30H,17-22,29H2,1-5H3,(H,46,48)(H,47,54)(H2,49,50,55)
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US Patent
n/an/a 24n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...

US Patent US9796742 (2017)


BindingDB Entry DOI: 10.7270/Q2KW5J5M
More data for this
Ligand-Target Pair