Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM354323'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM354323 (1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...) Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CP(C)(C)=O)c4)C(C)C)c4ccccc34)ccn2)cc(OCCN2CCOCC2)c1 Show InChI InChI=1S/C44H50N7O6P/c1-30(2)40-28-43(51(49-40)33-10-8-9-31(23-33)29-58(4,5)53)48-44(52)47-39-13-14-41(38-12-7-6-11-37(38)39)57-34-15-16-45-42(27-34)46-32-24-35(54-3)26-36(25-32)56-22-19-50-17-20-55-21-18-50/h6-16,23-28,30H,17-22,29H2,1-5H3,(H,45,46)(H2,47,48,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Limited; Topivert Pharma Limited US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...				US Patent US9796742 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J5M
					More data for this Ligand-Target Pair