BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM354332'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM354332
PNG
(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Show SMILES COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CP(C)(C)=O)c4)C(C)(C)C)c4ccccc34)n2)cc(OC)c1
Show InChI InChI=1S/C45H54N7O8P/c1-45(2,3)40-29-41(52(51-40)33-12-10-11-31(25-33)30-61(6,7)54)49-44(53)48-38-15-16-39(37-14-9-8-13-36(37)38)60-42-17-18-46-43(50-42)47-32-26-34(56-5)28-35(27-32)59-24-23-58-22-21-57-20-19-55-4/h8-18,25-29H,19-24,30H2,1-7H3,(H,46,47,50)(H2,48,49,53)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 71n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...

US Patent US9796742 (2017)


BindingDB Entry DOI: 10.7270/Q2KW5J5M
More data for this
Ligand-Target Pair