Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50352582'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50352582 (CHEMBL1825162 | US8772288, 52) Show SMILES Cc1ccc(cc1-c1ncc2c(NC(=O)C22CCCC2)n1)C(=O)NC1CC1 Show InChI InChI=1S/C21H22N4O2/c1-12-4-5-13(19(26)23-14-6-7-14)10-15(12)17-22-11-16-18(24-17)25-20(27)21(16)8-2-3-9-21/h4-5,10-11,14H,2-3,6-9H2,1H3,(H,23,26)(H,22,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	72	n/a	n/a	n/a	n/a	7.5	25
Almirall, S.A. US Patent					Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...				US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50352582 (CHEMBL1825162 | US8772288, 52) Show SMILES Cc1ccc(cc1-c1ncc2c(NC(=O)C22CCCC2)n1)C(=O)NC1CC1 Show InChI InChI=1S/C21H22N4O2/c1-12-4-5-13(19(26)23-14-6-7-14)10-15(12)17-22-11-16-18(24-17)25-20(27)21(16)8-2-3-9-21/h4-5,10-11,14H,2-3,6-9H2,1H3,(H,23,26)(H,22,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assay				Bioorg Med Chem Lett 21: 5270-3 (2011) Article DOI: 10.1016/j.bmcl.2011.07.033 BindingDB Entry DOI: 10.7270/Q2KD1Z8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50352582 (CHEMBL1825162 | US8772288, 52) Show SMILES Cc1ccc(cc1-c1ncc2c(NC(=O)C22CCCC2)n1)C(=O)NC1CC1 Show InChI InChI=1S/C21H22N4O2/c1-12-4-5-13(19(26)23-14-6-7-14)10-15(12)17-22-11-16-18(24-17)25-20(27)21(16)8-2-3-9-21/h4-5,10-11,14H,2-3,6-9H2,1H3,(H,23,26)(H,22,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISA				Bioorg Med Chem Lett 21: 5270-3 (2011) Article DOI: 10.1016/j.bmcl.2011.07.033 BindingDB Entry DOI: 10.7270/Q2KD1Z8K
					More data for this Ligand-Target Pair