Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50376237'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50376237 (CHEMBL409328) Show SMILES CNC(=O)c1ccc(C)c(Nc2ncnc3n(ncc23)-c2c(C)cc(C)cc2C)c1 |(20.89,3.58,;19.55,4.34,;18.22,3.57,;18.22,2.03,;16.89,4.34,;16.88,5.89,;15.54,6.66,;14.21,5.89,;12.88,6.65,;14.21,4.34,;12.88,3.57,;12.88,2.03,;14.2,1.27,;14.21,-.26,;12.87,-1.04,;11.54,-.27,;10.07,-.74,;9.17,.5,;10.07,1.75,;11.53,1.27,;9.29,-2.07,;7.75,-2.05,;6.99,-.71,;6.97,-3.38,;7.73,-4.72,;6.95,-6.04,;9.27,-4.73,;10.05,-3.4,;11.59,-3.41,;15.54,3.57,)| Show InChI InChI=1S/C23H24N6O/c1-13-8-15(3)20(16(4)9-13)29-22-18(11-27-29)21(25-12-26-22)28-19-10-17(23(30)24-5)7-6-14(19)2/h6-12H,1-5H3,(H,24,30)(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated myelin basic protein phosphorylation				Bioorg Med Chem Lett 18: 2652-7 (2008) Article DOI: 10.1016/j.bmcl.2008.03.019 BindingDB Entry DOI: 10.7270/Q2C53MR6
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