Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50392171'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392171 (CHEMBL2152940) Show SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H19F2NO3/c24-16-4-8-22(21(25)12-16)26-17-5-7-19-15(11-17)2-1-14-3-6-18(29-10-9-27)13-20(14)23(19)28/h3-8,11-13,26-27H,1-2,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392171 (CHEMBL2152940) Show SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H19F2NO3/c24-16-4-8-22(21(25)12-16)26-17-5-7-19-15(11-17)2-1-14-3-6-18(29-10-9-27)13-20(14)23(19)28/h3-8,11-13,26-27H,1-2,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392171 (CHEMBL2152940) Show SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H19F2NO3/c24-16-4-8-22(21(25)12-16)26-17-5-7-19-15(11-17)2-1-14-3-6-18(29-10-9-27)13-20(14)23(19)28/h3-8,11-13,26-27H,1-2,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha-dependent TNFalpha production in human whole blood				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392171 (CHEMBL2152940) Show SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H19F2NO3/c24-16-4-8-22(21(25)12-16)26-17-5-7-19-15(11-17)2-1-14-3-6-18(29-10-9-27)13-20(14)23(19)28/h3-8,11-13,26-27H,1-2,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISA				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair