Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50494271'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494271 (CHEMBL3087480) Show SMILES CN(C)CCOc1ccc2c(COc3cc(Nc4ccc(F)cc4F)ccc3C2=O)c1 Show InChI InChI=1S/C24H22F2N2O3/c1-28(2)9-10-30-18-5-7-19-15(11-18)14-31-23-13-17(4-6-20(23)24(19)29)27-22-8-3-16(25)12-21(22)26/h3-8,11-13,27H,9-10,14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494271 (CHEMBL3087480) Show SMILES CN(C)CCOc1ccc2c(COc3cc(Nc4ccc(F)cc4F)ccc3C2=O)c1 Show InChI InChI=1S/C24H22F2N2O3/c1-28(2)9-10-30-18-5-7-19-15(11-18)14-31-23-13-17(4-6-20(23)24(19)29)27-22-8-3-16(25)12-21(22)26/h3-8,11-13,27H,9-10,14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISA				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair