Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50494277'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494277 (CHEMBL3086693) Show SMILES Nc1ccc2COc3cc(Nc4cc(F)c(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C20H13F3N2O2/c21-15-7-17(23)18(8-16(15)22)25-12-3-4-13-19(6-12)27-9-10-1-2-11(24)5-14(10)20(13)26/h1-8,25H,9,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494277 (CHEMBL3086693) Show SMILES Nc1ccc2COc3cc(Nc4cc(F)c(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C20H13F3N2O2/c21-15-7-17(23)18(8-16(15)22)25-12-3-4-13-19(6-12)27-9-10-1-2-11(24)5-14(10)20(13)26/h1-8,25H,9,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISA				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair