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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50505903'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50505903
PNG
(CHEMBL4462636)
Show SMILES Cc1ccc(cc1NC(=O)c1ccc(s1)-c1ccccc1Cl)C(=O)N[C@@H](CCC1CCCCC1)C(N)=O |r|
Show InChI InChI=1S/C29H32ClN3O3S/c1-18-11-13-20(28(35)32-23(27(31)34)14-12-19-7-3-2-4-8-19)17-24(18)33-29(36)26-16-15-25(37-26)21-9-5-6-10-22(21)30/h5-6,9-11,13,15-17,19,23H,2-4,7-8,12,14H2,1H3,(H2,31,34)(H,32,35)(H,33,36)/t23-/m0/s1
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PC cid
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Article
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n/an/a 15n/an/an/an/an/an/a



Johann Wolfgang Goethe-University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...

J Med Chem 62: 10757-10782 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01227
BindingDB Entry DOI: 10.7270/Q2NV9NJK
More data for this
Ligand-Target Pair