Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50524520'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50524520 (CHEMBL4435922) Show SMILES CSc1nc(c([nH]1)-c1ccnc(NC(=O)[C@H]2C[C@H](Cl)C2)c1)-c1ccc(F)cc1 |r,wU:15.15,wD:17.18,(60.15,-5.52,;59.38,-6.85,;57.85,-6.86,;57.09,-5.51,;55.58,-5.82,;55.4,-7.35,;56.8,-7.99,;54.07,-8.1,;52.74,-7.31,;51.4,-8.07,;51.38,-9.61,;52.72,-10.39,;52.7,-11.93,;54.03,-12.71,;54.02,-14.25,;55.37,-11.95,;55.77,-10.47,;57.26,-10.88,;58.6,-10.12,;56.85,-12.37,;54.05,-9.63,;54.45,-4.78,;54.79,-3.28,;53.66,-2.23,;52.19,-2.69,;51.05,-1.65,;51.85,-4.21,;52.99,-5.24,)| Show InChI InChI=1S/C20H18ClFN4OS/c1-28-20-25-17(11-2-4-15(22)5-3-11)18(26-20)12-6-7-23-16(10-12)24-19(27)13-8-14(21)9-13/h2-7,10,13-14H,8-9H2,1H3,(H,25,26)(H,23,24,27)/t13-,14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISA				Eur J Med Chem 175: 309-329 (2019) Article DOI: 10.1016/j.ejmech.2019.04.035 BindingDB Entry DOI: 10.7270/Q29C71T1
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