Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50537605'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537605 (CHEMBL4635980 | US11149020, Compound 28 (MW-118)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C22H22N6/c1-27-10-12-28(13-11-27)21-15-19(16-4-7-23-8-5-16)22(26-25-21)18-2-3-20-17(14-18)6-9-24-20/h2-9,14-15,24H,10-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	518	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537605 (CHEMBL4635980 | US11149020, Compound 28 (MW-118)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C22H22N6/c1-27-10-12-28(13-11-27)21-15-19(16-4-7-23-8-5-16)22(26-25-21)18-2-3-20-17(14-18)6-9-24-20/h2-9,14-15,24H,10-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190A				J Med Chem 62: 5298-5311 (2019) Article DOI: 10.1021/acs.jmedchem.9b00058 BindingDB Entry DOI: 10.7270/Q24170ZD
					More data for this Ligand-Target Pair