Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM84789'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM84789 ((9b) BIRB796) Show SMILES Cc1ccc(cc1C(O)=O)C(=O)NC(O)(NC(=O)NCc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccccc1)C(C)(C)C)C1CCCC1 Show InChI InChI=1S/C38H45N7O6/c1-24-15-18-26(21-30(24)34(47)48)33(46)42-38(51,27-11-9-10-12-27)44-37(5,50)39-23-25-16-19-29(20-17-25)45-32(22-31(43-45)36(2,3)4)41-35(49)40-28-13-7-6-8-14-28/h6-8,13-22,27H,9-12,23H2,1-5H3,(H,47,48)(H2,40,41,49)(H3,39,42,44,46,50,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	7.5	25
Pfizer Inc.					Assay Description Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...				Chem Biol Drug Des 74: 547-59 (2009) Article DOI: 10.1111/j.1747-0285.2009.00884.x BindingDB Entry DOI: 10.7270/Q2930RPH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM84789 ((9b) BIRB796) Show SMILES Cc1ccc(cc1C(O)=O)C(=O)NC(O)(NC(=O)NCc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccccc1)C(C)(C)C)C1CCCC1 Show InChI InChI=1S/C38H45N7O6/c1-24-15-18-26(21-30(24)34(47)48)33(46)42-38(51,27-11-9-10-12-27)44-37(5,50)39-23-25-16-19-29(20-17-25)45-32(22-31(43-45)36(2,3)4)41-35(49)40-28-13-7-6-8-14-28/h6-8,13-22,27H,9-12,23H2,1-5H3,(H,47,48)(H2,40,41,49)(H3,39,42,44,46,50,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	7.5	25
Pfizer Inc.					Assay Description Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...				Chem Biol Drug Des 74: 547-59 (2009) Article DOI: 10.1111/j.1747-0285.2009.00884.x BindingDB Entry DOI: 10.7270/Q2930RPH
					More data for this Ligand-Target Pair