Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 6' and Ligand = 'BDBM50553820'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 6 (Homo sapiens (Human))	BDBM50553820 (CHEMBL4786970) Show SMILES CN1CCC(CC1)n1cc(Nc2ncc3nnn(-c4ccn(C)n4)c3n2)cn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127551 BindingDB Entry DOI: 10.7270/Q2057KKN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Homo sapiens (Human))	BDBM50553820 (CHEMBL4786970) Show SMILES CN1CCC(CC1)n1cc(Nc2ncc3nnn(-c4ccn(C)n4)c3n2)cn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127551 BindingDB Entry DOI: 10.7270/Q2057KKN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Homo sapiens (Human))	BDBM50553820 (CHEMBL4786970) Show SMILES CN1CCC(CC1)n1cc(Nc2ncc3nnn(-c4ccn(C)n4)c3n2)cn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127551 BindingDB Entry DOI: 10.7270/Q2057KKN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Homo sapiens (Human))	BDBM50553820 (CHEMBL4786970) Show SMILES CN1CCC(CC1)n1cc(Nc2ncc3nnn(-c4ccn(C)n4)c3n2)cn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127551 BindingDB Entry DOI: 10.7270/Q2057KKN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Homo sapiens (Human))	BDBM50553820 (CHEMBL4786970) Show SMILES CN1CCC(CC1)n1cc(Nc2ncc3nnn(-c4ccn(C)n4)c3n2)cn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to wild-type human partial length ERK3 (M1 to P413 residues) expressed in bacterial expression system by kinomescan method				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127551 BindingDB Entry DOI: 10.7270/Q2057KKN
					More data for this Ligand-Target Pair